个人简介
徐莺,博士,教授。专注于利用植物分子生物学和生物技术研究,对我国西南地区的资源植物进行开发利用研究,特别是利用组学技术和生物信息学技术对具有抗肿瘤、抗病毒的麻疯树核糖体失活蛋白资源进行挖掘和作用机制研究。近年来,主持国家自然科学基金2项,国际合作项目1项以及省级科技攻关项目多项,已在国内外重要学术刊物上发表论文50余篇,出版学术著作2部,获得国家发明专利授权7项,在国际性学术会议上宣讲论文4次。
主讲课程
《分子生物学》(双语)(本科生)
《植物发育生物学》(硕士研究生)
《生命周期分析》(硕士研究生)
研究方向
资源植物天然活性蛋白(肽类)筛选及功能和机制研究
植物油脂成分的分子合成机理及生物改良技术研究
联系方式
工作邮箱:xuying@scu.edu.cn
近期主持项目
1.四川省科技厅重点研发项目(2021年)
2.国家自然科学基金面上项目(2019年)
3.成都大学农业部杂粮加工重点实验室开放课题(2019年)
4.beat365校地合作项目(2018年)
5.欧盟国际合作项目(2017年)
发表文章
LRP1-mediated endocytosis may be the main reason for the difference in cytotoxicity of Curcin and Curcin C on U2OS osteosarcoma cells, Toxins (Basel), 2022 Nov 8;14(11):771. doi: 10.3390/toxins14110771
Curcin C inhibit osteosarcoma cell line U2OS proliferation by ROS induced apoptosis, autophagy and cell cycle arrest through activating JNK signal pathway,INT J BIOL MACROMOL,2022,195:433-439
Enhancement of tobacco (Nicotiana tabacum L.) seed lipid content for biodiesel production by crispr-cas9-mediated knockout of NtAn1,FRONT PLANT SCI,2021,11:599474doi: 10.3389/fpls.2020.599474.
FAX2 mediates fatty acid export from plastids in developing Arabidopsis seeds,PLANT CELL PHYSIOL,2019,60(10):2231–2242
Isolation and characterization of a Curcin promoter from Jatropha curcas L. and its regulation of gene expression in transgenic tobacco plants, PLANT MOL BIOL REP, 2009, 27:275–281
Regulation of trichome development in tobacco by JcZFP8, a C2H2 zinc finger protein gene from Jatropha curcas L., Gene, 2018, 658:47–53
Response of alternative splice isoforms of OsRad9 gene from Oryza sativa to environmental stress, Z NATURFORSCH C, 2017,72:325-334
Curcin C, a novel type I ribosome-inactivating protein from the post-germinating cotyledons of Jatropha curcas, Amino Acids, 2017 Sep;49(9):1619-1631. doi: 10.1007/ s00726-017- 2456-8
Characterization and expression profile of a phenylalanine ammonialyase gene from Jatropha curcas L., Mol. Bio. Rept., 2012, 39: 3443-3452
Molecular cloning, characterization and expression of cDNA encoding translationally controlled tumor protein (TCTP) from Jatropha curcas L., Mol. Bio. Rept., 2011, 38: 3107-3112
Isolation and characterization of a curcin promoter from Jatropha curcas L. and its regulation of gene expression in transgenic tobacco plants, Plant Mol. Bio. Rept., 2009, 27: 275-281
A ribosome-inactivating protein (curcin 2) induced from Jatropha curcas can reduce viral and fungal infection in transgenic tobacco, Plant Growth Regul., 2008, 54:1
授权专利
超长基因在植物中快速表达的方法(ZL 202110018664.0)
一种缓解高浓度稀土元素胁迫下植物生长受阻的方法及应用(ZL 202111308208.6)
麻疯树核糖体失活蛋白及其分离纯化方法与应用(ZL 201710217471.1)
烟草C2H2型锌指蛋白基因Nt540的应用(ZL 201710157893.4)
一种以珙桐叶片为外植体的组织培养获得珙桐再生苗的方法(ZL 201210457129.6)
一种利用麻疯树子叶再生根诱导芽的快繁方法(ZL201310336772.8)
麻疯树种仁毒蛋白的分离纯化方法(ZL 201010115477.6)